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　　姓名：王琛

　　性別：男

　　醫(yī)師級(jí)別：執(zhí)業(yè)醫(yī)師

　　執(zhí)業(yè)類(lèi)別：臨床

　　執(zhí)業(yè)地點(diǎn)：上海市

　　執(zhí)業(yè)證書(shū)編碼：110310000042068

　　主要執(zhí)業(yè)機(jī)構(gòu)：上海交通大學(xué)醫(yī)學(xué)院附屬第九人民醫(yī)院

　　執(zhí)業(yè)范圍：外科專(zhuān)業(yè)

　　發(fā)證(批準(zhǔn))機(jī)關(guān)：上海市衛(wèi)生健康委員會(huì)

　　信息來(lái)源：國(guó)家衛(wèi)生健康委員會(huì)

暫時(shí)沒(méi)有內(nèi)容

　　上海交通大學(xué)醫(yī)學(xué)院附屬第九人民醫(yī)院 整復(fù)外科

　　教育部學(xué)位中心評(píng)審專(zhuān)家，國(guó)家自然科學(xué)基金評(píng)審專(zhuān)家。入選交大醫(yī)學(xué)院優(yōu)秀青年教師和九院優(yōu)秀青年骨干，主持省部級(jí)課題8項(xiàng)，參與“973”、“863”計(jì)劃等多個(gè)項(xiàng)目的研究，累及發(fā)表學(xué)術(shù)論文30余篇，其中SCI論文22篇（第一/通訊作者），參編專(zhuān)著3部?？蒲谐晒?/p>

　　主要發(fā)表文章：

　　1. Wang C, Cen L, Yin S, Liu Q, Liu W, Cao Y, Cui L. A small diameter elastic blood vessel wall prepared under pulsatile conditions from polyglycolic acid mesh and smooth muscle cells differentiated from adipose-derived stem cells, Biomaterials, 2010,31(4):621-630.

　　2. Wang C, Yin S, Cen L, Liu Q, Liu W, Cao Y, Cui L. Differentiation of adipose derived stem cells into contractile smooth muscle cells induced by TGF-β1 and BMP4, Tissue Eng Part A, 2010,16(4):1201-1213.

　　3. Yin S, Cen L, Wang C, Zhao G, Sun J, Liu W, Cao Y, Cui L. Chondrogenic transdifferentiation of human dermal fibroblasts stimulated with cartilage derived morphogenetic protein1, Tissue Eng Part A,2010,16(5):1633-1643.

　　4. Wang C, Guo F, Zhou H, Zhang Y, Xiao Z, Cui L. Proteomic profiling of tissue-engineered blood vessel walls constructed by adipose-derived stem cells, Tissue Eng Part A, 2013, 19(3-4):415-425.

　　5. Wang X,?Qian Y,?Jin R,?Wo Y,?Chen J,?Wang C,?Wang D. Effects?of?TRAP-1-like?protein?(TLP)?gene?on?collagen?synthesis?induced?by?TGF-β/Smad?signaling?in?humandermal?fibroblasts, PLoS One,2013,8(2):e55899.

　　6. Gu H, Xiong Z, Xu J, Li G, Wang C. Clinical and anatomical study of the distally based lesser saphenous veno-lateral sural neurocutaneous flap for lower extremity coverage, J Orthop Sci, 2013,18(5):740-748. (corresponding author)

　　7. Gong L, Wang C, Sun Q, Li G, Wang D. Effects of human adipose derived stem cells on the viability of rabbit random pattern flaps, Cytotherapy, 2014,16(4):496-507. (co-author)

　　8. Gong L, Zhou X, Wu Y, Zhang Y, Wang C, Zhou H, Guo F, Cui L. Proteomic Analysis Profile of Engineered Articular Cartilage with Chondrogenic Differentiated Adipose Tissue-Derived Stem Cells Loaded Polyglycolic Acid Mesh for Weight-Bearing Area Defect Repair,Tissue Eng Part A, 2014,20(3-4):575-87.

　　9. Gu H, Xiong Z, Yin X, Li B, Mei N, Li G, Wang C. Bone regeneration in a rabbit ulna defect model: use of allogeneic adipose-derived stem cells with low immunogenicity, Cell Tissue Res,2014,358(2):453-64. (corresponding author)

　　10. Wang C, Xiong Z, Xu J, Zhang L, Huang H, Li G. The distally based lateral sural neuro-lesser saphenous veno-fasciocutaneous flap: anatomical basis and clinical applications, J Orthop Traumatol, 2014,15(3):215-23.

　　11. Wang C, Cai Y, Zhang Y, Xiong Z, Li G, Cui L. Local injection of deferoxamine improves neovascularization in ischemic diabetic random flap by increasing HIF-1α and VEGF expression. PLoS One. 2014;9(6):e100818.

　　12.Wang X,?Chu J,?Wen C,?Fu S,?Qian Y,?Wo Y,?Wang C,?Wang D. Functional?characterization?of?TRAP1-like?protein?involved?in?modulating?fibrotic?processes?mediated?by TGF-β/Smad?signaling?in?hypertrophic?scar?fibroblasts. Exp Cell Res.2015;332(2):202-11. (corresponding author)

　　13. Wen C, Yan H, Fu S, Qian Y, Wang D, Wang C, Allogeneic Adipose-derived Stem Cells Regenerate Bone in a Critical-sized Ulna Segmental Defect. Exp Biol Med .?2015 Mar 27. (corresponding author)

　　14． Lv Y, Cao D, Guo F, Qian Y, Wang C, Wang D. Abdominal wall reconstruction using a combination of free tensor fasciae lata and anterolateral thigh myocutaneous flap: a prospective study in 16 patients.Am J Surg.?2015;210(2):365-73. (corresponding author)

　　15. Zhou R, Zhang Q, Zhang Y, Fu S, Wang C.Aberrant miR-21 and miR-200b expression and its pro-fibrotic potential in hypertrophic scars. Exp Cell Res. 2015 Oct 20. (corresponding author)

　　16. 王琛，徐靜，張莉，熊竹友，李光早。指背血管蒂島狀皮瓣應(yīng)用解剖。 中國(guó)臨床解剖學(xué)雜志。2006;24(5):514-517。

　　17. 王琛，郭芳芳，張昀，等。 應(yīng)用脂肪干細(xì)胞構(gòu)建小口徑組織工程血管平滑肌層的實(shí)驗(yàn)研究. 組織工程與重建外科雜志. 2012,8(5):249-255

　　18.熊竹友，方小魁，徐靜，張莉，王琛，李光早。同種異體脂肪干細(xì)胞復(fù)合脫鈣骨修復(fù)大鼠尺骨缺損。組織工程與重建外科雜志,2013,9(5):245-251.（通信作者）

　　19. 張奇，王琛。microRNA-21調(diào)控TGF-β通路促進(jìn)增生性瘢痕形成的機(jī)制研究。組織工程與重建外科雜志,2014,10(6):318-323. （通信作者）

　　20．張奇，王琛。VSD技術(shù)臨床應(yīng)用研究現(xiàn)狀. 中華醫(yī)學(xué)雜志，2014,11(10):52-56。（通信作者）

　　21. 張奇，王琛。miRNA參與調(diào)控皮膚創(chuàng)傷修復(fù)的發(fā)生發(fā)展。醫(yī)學(xué)美學(xué)美容，2015,1(1):35-36。（通信作者）

　　承擔(dān)課題

　　1. 上海市自然科學(xué)基金：應(yīng)用脂肪干細(xì)胞構(gòu)建雙層結(jié)構(gòu)的組織工程化血管修復(fù)小口徑動(dòng)脈缺損的實(shí)驗(yàn)研究（11ZR1420300）

　　2. 國(guó)家自然科學(xué)基金青年基金：力學(xué)刺激誘導(dǎo)miR-100誘導(dǎo)脂肪干細(xì)胞向平滑肌細(xì)胞分化的作用和機(jī)制（810201204）

　　3. 上海高校青年教師科研專(zhuān)項(xiàng)基金：miR-21調(diào)控Smad7基因表達(dá)在增生性瘢痕形成中的作用及機(jī)制（ZZjdyx12100）

　　4. 上海交大醫(yī)學(xué)院優(yōu)秀青年教師人才計(jì)劃：miR-31/FIH軸調(diào)控HIF-1α通路促進(jìn)增生性瘢痕發(fā)展的機(jī)制研究

　　5. 第五屆“九院優(yōu)青培養(yǎng)計(jì)劃”： miR-21調(diào)控TGF-β通路在增生性疤痕形成中的作用及機(jī)制

　　中華醫(yī)學(xué)會(huì) (上海) 分會(huì) 副主任委員